User Case: Is the Tamiflu efficient to diminish the percentage of secondary complications in children with flu?

This user case is inspired by a search tutorial for Pubmed (see page 61) brought to our knowledge by María, Medical Librarian from Torrevieja Hospital (Spain). We found it interesting to show how novoseek provides results as satisfactory as Pubmed in a simple and quick way.

1. We first search for « tamiflu » in novoseek.There are 840 results in pubmed and 144 in free full text to date.
   
2. Looking in the search details we notice that our search has been mapped to pharmacological substance « tamiflu ».
   Clicking on the the term tamiflu pops up a window with complementary information. This is handy to know the synonyms (alternative names) to Tamiflu : Oseltamivir phosphate , GS 4104 are some of them.

3. We need to look for influenza disease to keep building our search.Obviously, it should appear in the first relevant related concepts to the previous search. Indeed, it is the first related disease to the search Tamiflu. Clicking on it will add it directly to the current search (alternatively you can click on the « i » icon and click on « add filter » as shown on image). The search is now refined and we have gone from 840 results to 639 results in Pubmed.
   
   
   In this case, we are looking for Meta-Analysis publications. In science, “meta-analysis does more than just combine the effect sizes of a set of studies. It can test if the studies’ outcomes show more variation than the variation that is expected because of sampling different research participants” as explained in the Wikipedia. This should help us find publications showing the efficiency of Tamiflu to diminish the percentage of secondary complications.
4. We now need to select the publication type (or type or article).We click on the « bibliographics tab » and where publication type is, we click on the « more » button. Where « Meta Analysis » appears, we click on that term which is directly added to the current search. We now have gone from 639 results to 9 results in Pubmed.
   
   
5. The results are very satisfactory as they contain the same publications as in Pubmed. Should we need to look specifically for publication mentioning children, look for the filter “Homo Sapiens” in the related concepts tab on the left and add it to your search. We now have 5 results in Pubmed.
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We can compare now these results to Pubmed’s and we notice that we have the 3 publications found in Pubmed in novoseek results. The advantage with novoseek is that we have performed a complex search in a simple way and in no time.

We recommend you to read:

• Why Publication Types matter when looking for relevant scientific literature in Pubmed
• A user case inspired by Flash Forward and a poll
• Perform an effective search with novoseek: Asperger Syndrome and Bipolar disorder in autism
• How to create biomedical gadgets in a few steps
• The importance of context in text disambiguation